You should always consider using the Object provided by the MV* framework. If the JS framework doesn’t have a built-in support for communicating with the server (which I highly doubt), you can opt to work directly with the low-level methods of the XMLHttpRequest object itself or use a general utility library such as JQuery.
On the Node.js environment
XMLHttpRequest is a built-in object in web browsers.
It is not distributed with Node; you have to install it separately using npm.
That said, Node comes with the http module which is the normal tool for choice for making HTTP requests from Node.
Eric's playground 